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Glutaminyl Cyclase Inhibitor3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101282
    Glutaminyl Cyclase Inhibitor 3

    		Amyloid-β Neurological Disease
    Glutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. Glutaminyl Cyclase-IN-1 (compound 212) significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions .
    <em>Glutaminyl</em> <em>Cyclase</em> <em>Inhibitor 3</em>

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